Design, Synthesis, and Self-Assembly of Polymers with Tailored Graft Distributions Alice B. Chang, Tzu-Pin Lin, Niklas B. Thompson, Shao-Xiong Luo, Allegra L. Liberman-Martin, Hsiang-Yun Chen, Byeongdu Lee, and Robert H. Grubbs* J Am Chem Soc 2017 … [Continue reading]
The Metathesis Reaction in Drug Discovery and Development – A Review of Recent Patent Literature David L Hughes*, Philip Wheeler*, and Doina Ene Org Proc Res Dev 2017 ASAP A thorough review of patent literature (01/2016-08/2017) focused on the … [Continue reading]
Decomposition of Olefin Metathesis Catalysts by Brønsted Base: Metallacyclobutane Deprotonation as a Primary Deactivating Event Gwendolyn A Bailey, Justin Alexander MacDonald Lummiss, Marco Foscato, Giovanni Occhipinti, Robert McDonald, Vidar … [Continue reading]
Total synthesis and cytotoxic activity of 5′-hydroxyzearalenone and 5′β-hydroxyzearalenone Aticha Thiraporn, Vatcharin Rukachaisirikul, Panata Iawsipo, Tatiyar Somwang, and Kwanruthai Tadpetch* Eur J Org Chem 2017 … [Continue reading]
Loss and Reformation of Ruthenium Alkylidene: Connecting Olefin Metathesis, Catalyst Deactivation, Regeneration, and Isomerization Julien Engel, Wietse Smit, Marco Foscato, Giovanni Occhipinti,* Karl W. Törnroos and Vidar R. Jensen* J Am Chem … [Continue reading]
Single polymer growth dynamics Chunming Liu, Kaori Kubo, Endian Wang, Kyu-Sung Han, Feng Yang, Guanqun Chen, Fernando A. Escobedo,* Geoffrey W. Coates,* Peng Chen* Science 2017 358 352-355 Norbornene-Functionalized PEO-b-PCL: A Versatile … [Continue reading]
Synthesis and Evaluation of Sterically Demanding Ruthenium Dithiolate Catalysts for Stereoretentive Olefin Metathesis T. Patrick Montgomery, Jessica M. Grandner, K. N. Houk, and Robert H. Grubbs* Organometallics 2017 ASAP Synthesis and … [Continue reading]
Total Synthesis of Kanamienamide D. Prabhakar Reddy, Ning Zhang, Zhimei Yu, Zhen Wang, and Yun He* J Org Chem 2017 ASAP A 1,2-Dicarbadodecaborane(12)-1,2-Dithiolate Chelating Ruthenium Carbene Catalyst for Highly Z Selective Olefin … [Continue reading]
Formal total synthesis of stigmatellin A J. S. Yadav,* G.Revathi, B. V. Subba Reddy Tetrahedron Letters 2017 58 3943-3946 Synthesis of Tricyclic Units of Indole Alkaloids: Application of Fischer Indolization and Olefin … [Continue reading]
Mid-chain carboxylic acids by catalytic refining of microalgae oil Julia Zimmerer, Lara Williams, Dennis Pingen and Stefan Mecking* Green Chem 2017 ASAP Model studies for the preparation of Oxepanes and fused compounds via tandem 4+3 … [Continue reading]
Synthesis of Amphiphilic Homopolymers and Their Self-Assembly into Acid-Responsive Polymeric Micelles Hyeongju Noh, Ho-Joong Kim,* Si Kyung Yang* J Polym Sci A 2017 ASAP Synthesis and One-Dimensional Assembly of Cylindrical Polymer … [Continue reading]