Urbina-Blanco, C. A.; Poater, A.; Lebl, T.; Manzini, S.; Slawin, A. M. Z.; Cavallo, L.; Nolan, S. P. The Activation Mechanism of Ru-Indenylidene Complexes in Olefin Metathesis. J. Am. Chem. Soc. 2013, 135, 7073-7079. Recent literature accounts … [Continue reading]
Grau, E.; Mecking, S. “Polyterpenes by ring opening metathesis polymerization of caryophyllene and humulene” Green Chemistry 2013, 15, 1112-1115 Polymers are an indispensable commodity within modern society found in all sectors of a consumer … [Continue reading]
Despite the huge advances in the area of olefin metathesis, better catalysts are still sought to increase the efficiency of ring closing metathesis (RCM) reactions and make them more applicable in industry1. Recently, several modified second-gen … [Continue reading]
Wathier, M.; Lakin, B. A.; Bansal, P. N.; Stoddart, S. S.; Snyder, B. D.; Grinstaff, M. W. “A Large-Molecular-Weight Polyanion, Synthesized via Ring-Opening Metathesis Polymerization, as a Lubricant for Human Articular Cartilage” J. Am. Chem. Soc. … [Continue reading]
The 245th ACS National Meeting & Exhibition is right around the corner and will be held in New Orleans, Louisiana from April 7-11, 2013. I guess it’s somewhat fitting that I happen to be writing this post on Fat Tuesday...#MardiGras! The theme of … [Continue reading]
Khalimon, A.Y; Leitao, E.M.; Piers, W. E. “Photogeneration of a Phosphonium Alkylidene Olefin Metathesis Catalyst” Organometallics 2012, 31, 5634-5637. DOI: 10.1021/om3005965 Chemists are always searching for a finely tunable, robust catalyst. … [Continue reading]
Kong, J.; Chen; C.; Balsells-Padros; J., Cao, Y.; Dunn, R. F.; Dolman, S. J.; Janey, J.; Li, H.; and Zakuto, M.J. “Synthesis of the HCV Protease Inhibitor Vaniprevir (MK-7009) Using Ring-Closing Metathesis Reaction” J. Org. Chem. 2012, 77, … [Continue reading]
Ohlmann, D. M.; Tschauder, N.; Stockis, J.-P.; Gooßen, Dierker, M.; Gooßen, L. J. “Isomerizing Olefin Metathesis as a Strategy To Access Defined Distributions of Unsaturated Compounds from Fatty Acids” J. Am. Chem. Soc. 2012, 134, 13716-13729. As … [Continue reading]
Amakawa, K.; Wrabetz, S.; Kröhnert, J.; Tzolova-Müller, G. Schlögl, R.; Trunschke, A. “In Situ Generation of Active Sites in Olefin Metathesis” J. Am. Chem. Soc. 2012, 134, 11462-11473. Heterogeneous, silica-supported tungsten catalysts are used to … [Continue reading]
Park, Hyeon; Choi, Tae-Lim. “Fast Tandem Ring-Opening/Ring-Closing Metathesis Polymerization from a Monomer Containing Cyclohexene and Terminal Alkyne” J. Am. Chem. Soc. 2012, 134 (17), 7270-7273. DOI: 10.1021/ja3017335 Sometimes two wrongs can … [Continue reading]
After the first generation of well-defined ruthenium metathesis catalysts were developed, most of the efforts in designing new catalysts concentrated on finding more and more reactive versions. However, more reactive catalysts are not suitable for … [Continue reading]