Acrylonitrile Cross-Metathesis

November 2, 2011

Miao, X.; Dixneuf, P.H.; Fischmeister, C.; Bruneau, C. “A green route to nitrogen-containing groups: the acrylonitrile cross-metathesis and applications to plant oil derivatives.” Green Chem., 2011, 13, 2258-2271. A straightforward route to organonitriles, versatile intermediates in organic synthesis, would be cross metathesis (CM) with acrylonitrile. Unfortunately, acrylonitrile is definitely not the best substrate for metathesis reactions. [...]

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Commercial Application of Metathesis: Elevance Plans for IPO

October 5, 2011

Elevance Renewable Sciences announced its intent to go public by filing an S-1 with the SEC last month. In the process, they hope to raise $100 million to fund continued R&D, capital expansion, and product development. Founded in 2007, Elevance developed from a partnership between Cargill and Materia to couple Cargill’s expertise in agricultural oils [...]

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Developments in Cis-Selective Ruthenium Olefin Metathesis Catalysts

September 21, 2011

Endo, K.; Grubbs, R. H.  “Chelated Ruthenium Catalysts for Z-Selective Olefin Metathesis.”  J. Am. Chem. Soc.,  2011, 133, 8525-8527. Recently, I wrote a post describing a series of Ru-olefin metathesis catalysts developed in the Grubbs’ laboratory, containing one sterically demanding X-type ligand as a replacement for the standard chloride ligand of the classic Grubbs-type catalyst. [...]

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