Determining the Double Bond Position with Cross Metathesis

December 15, 2011

Kwon, Y., Lee, S., Oh, D.-C. and Kim, S. (2011), Simple Determination of Double-Bond Positions in Long-Chain Olefins by Cross-Metathesis. Angewandte Chemie International Edition, 50: 8275–8278. doi: 10.1002/anie.201102634 The accurate determination of the double-bond position in unsaturated long-chain compounds remains a challenging task. Current analytical techniques rely on analyzing fragment ions by mass spectrometry, but [...]

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Ruthenacyclobutanes and Productive versus Degenerate Metathesis Events

November 17, 2011

Keitz, B. K.; Grubbs, R. H.  “Probing the Origin of Degenerate Metathesis Selectivity via Characterization and Dynamics of Ruthenacyclobutanes Containing Variable NHCs.”  J. Am. Chem. Soc., 2011, 133 (40), 16277-16284. Back in September of 2010, ATM’s very own Andy Nickel wrote a post on a publication from the Grubbs group describing non-productive events during ring-closing [...]

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Biological Properties of Grubbs and Hoveyda-Grubbs Catalysts

November 10, 2011

Oehninger, L., Alborzinia, H., Ludewig, S., Baumann, K., Wölfl, S. and Ott, I. (2011), From Catalysts to Bioactive Organometallics: Do Grubbs Catalysts Trigger Biological Effects?. ChemMedChem. doi: 10.1002/cmdc.201100308 Organometallic compounds are primarily used in catalysis, however, some of them have been found to have important biological properties as well. In the early 60s’, the discovery [...]

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