Relay Cross Metathesis for the Iterative Construction of Terpenoids and Synthesis of a Diterpene-Benzoate Macrolide of Biogenetic Relevance to the Bromophycolides Karim A. Bahou, D. Christopher Braddock,* Adam G. Meyer, and G. Paul Savage Org Lett 2020 22 8 3176-3179 Enantioselective formal synthesis of the marine macrolide (–)-callyspongiolide Aina Urbina, Núria Llor, Maria Vittoria Barbieri, […]

Syntheses of Complex Terpenes from Simple Polyprenyl Precursors Claire S. Harmange Magnani, Danny Q. Thach, Karl T. Haelsig, and Thomas J. Maimone* Acc Chem Res 2020 ASAP Total synthesis of prostratin, a bioactive tigliane diterpenoid: access to multi-stereocenter cyclohexanes from a phenol Guanghu Tong, Zhengwei Ding, Zhi Liu, You-Song Ding, Liang Xu,* Hailong Zhang, Pengfei […]

Stereoselective Synthesis of Conjugated Polyenes Based on Tethered Olefin Metathesis and Carbonyl Olefination: Application to the Total Synthesis of (+)-Bretonin B Kajsa Lood and Bernd Schmidt* J Org Chem 2020 ASAP A Relay Strategy Actuates Pre-Existing Trisubstituted Olefins in Monoterpenoids for Cross-Metathesis with Trisubstituted Alkenes Karim A. Bahou, D. Christopher Braddock,* Adam G. Meyer, G. […]

Synthesis of high-molecular weight poly(1,1-dimethyl-1-silapentene) by olefin metathesis polymerization in the presence of Grubbs catalysts Alexander Morontsev, Maria Gringolts*, Valentin Lakhtin, Eugene Finkelshtein J Organomet Chem 2020 ASAP Fast Oxygen Scavenging of Macroporous Poly(Norbornadiene) Prepared by Ring-Opening Metathesis Polymerization Efthymia Vakalopoulou, Sergey M. Borisov, and Christian Slugovc* Macromol Rapid Comm 2020 ASAP Robust Olefin Metathesis […]

A Macrocyclic Ruthenium Carbene for Size-Selective Alkene Metathesis Yutong Zhang and Steven T. Diver* J Am Chem Soc 2020 ASAP Synthesis and Activity of Six-Membered Cyclic Alkyl Amino Carbene-Ruthenium Olefin Metathesis Catalysts Adrian E. Samkian, Yan Xu, Scott C. Virgil, Ki-Young Yoon, and Robert H. Grubbs* Organometallics 2020 ASAP Latent Ruthenium Benzylidene Phosphite Complexes for […]

A Chiron Approach to the Stereoselective Total Synthesis of Phomonol and Phytotoxic Nonenolides Naveen Chandra and Rodney A. Fernandes* Eur J Org Chem 2020 ASAP Optimized Ring Closing Metathesis Reaction Conditions to Suppress Desallyl Side Products in the Solid Phase Synthesis of Cyclic Peptides involving Tyrosine(O-allyl) Solomon A. Gisemba and Jane V. Aldrich* J Org […]

Enol Ethers Are Effective Monomers for Ring-Opening Metathesis Polymerization: Synthesis of Degradable and Depolymerizable Poly(2,3-dihydrofuran) John D Feist, and Yan Xia* J Am Chem Soc 2020 ASAP Total Synthesis of (-)-Pepluanol B: Conformational Control of the Eight-Membered Ring System Jing Zhang, Meng Liu, Chuanhua Wu, Gaoyuan Zhao, Peiqi Chen, Lin Zhou, Xingang Xie, Ran Fang, […]

A Fluorescence-Based High-Throughput Screening Method for Olefin Metathesis Using a Ratiometric Fluorescent Probe Hyeongju Noh, Taeho Lim, Byoung Yong Park, and Min Su Han* Org Lett 2019 ASAP Unprecedented Selectivity of Ruthenium Iodide Benzylidenes in Olefin Metathesis Reactions Noy B. Nechmad, Ravindra Phatake, Elisa Ivry, Albert Poater, and N. Gabriel Lemcoff* Angew Chem Int Ed […]

Processable epoxy-telechelic polyalkenamers and polyolefins for photocurable elastomers Luke A. Kassekert, Claire E. Dingwell, Guilhem X. De Hoe and Marc A. Hillmyer* Polymer Chem 2019 ASAP Unintended Formation of a 26-Membered Cycle in the Course of a Novel Approach to Myricanol, a Strained [7,0]-Metacyclophane Paul Massé, Sabine Choppin,* Lucia Chiummiento,* Gilles Hanquet, Françoise Colobert Synlett […]

Synthesis and in vitro biological evaluation of 3-amino-3-deoxydihydrosphingosines and their analogues Jana Špaková Raschmanová, Miroslava Martinková,* Jozef Gonda, Martina Bago Pilátová, Juraj Kuchár, Dávid Jáger Tetrahedron 2019 ASAP Synthesis of Functionalized 6,5- and 7,5-Azabicycloalkane Amino Acids by Metathesis Reactions Massimo Serra,* Eric Bernardi, Ersilia De Lorenzi, and Lino Colombo J Org Chem 2019 ASAP Olefin […]

A Gentler Touch: Synthesis of Modern Ruthenium Olefin Metathesis Catalysts Sustained by Mechanical Force Nirmalya Mukherjee, Anna Marczyk, Grzegorz Szczepaniak, Adrian Sytniczuk, Anna Kajetanowicz, and Karol Grela* ChemCatChem 2019 ASAP This article details the application of mechanochemical synthesis to the prototypical transformations utilized in olefin metathesis catalyst synthesis. Two papers recently examined the mechanism of […]