Death by Carbonyl: Decomposition of Grubbs Catalysts by Primary Alcohols

In the “Devil’s Triangle” of catalysis there is a close inter-relationship between reactivity, selectivity and lifetime. Often, new catalysts are designed based on the promise of increased selectivity and reactivity while chemists cross their fingers and hope for longevity. By now it is well known that Grubbs metathesis catalysts are extremely active, chemoselective and robust, […]