Olefin Metathesis at the 248th ACS Meeting

by Adam Johns on July 30, 2014

The 248th American Chemical Society National Meeting and Exposition will be held in San Francisco, California from August 10-14, 2014. The theme of this fall’s meeting is “Chemistry and Global Stewardship.” As olefin metathesis has made significant contributions to the responsible management of world resources, it is fitting that many notable presentations will be given.

Of special note, Materia’s very own Dr. Mark Trimmer will be presenting a talk entitled “Olefin metathesis: Pushing the frontiers” describing the company’s contributions to the understanding and commercialization of metathesis (#534).

The meeting also features talks from Nobel Laureates Professor Bob Grubbs and Professor Dick Schrock. Prof. Grubbs’ first talk (#462) describes the variety of molecules made synthetically accessible with the expanding family of ruthenium catalysts while his second presentation (#189) focuses on his work with Z-selective catalysts from a computational perspective. Prof. Schrock’s presentation (#512) will describe his work controlling polymer stereochemistry with tungsten and molybdenum ring-opening metathesis catalysts.

Other interesting looking abstracts with an olefin metathesis focus include:

174 – Photolithographic olefin metathesis polymerization
Raymond Weitekamp, Harry Atwater, Robert Grubbs

photolithography meets olefin metathesis = PhotoLithographic Olefin Metathesis Polymerization (PLOMP)

292 – New ruthenium-based catalysts for Z-selective metathesis of hindered olefins
Brendan Quigley, Robert Grubbs

High yield and excellent selectivity for allylic-substituted olefins

417 – Ruthenium catalyzed synthesis of functionalized polypentenamers
Robert Tuba, Robert Grubbs

Recyclable functionalized polymers

764 – Cis-selective ring-opening metathesis polymerizations using ruthenium catalysts
Tonia S Ahmed, Vanessa M Marx

The effect of Z-selective catalyst structure on polymer microstructure

405 – Direct synthesis of Ruthenium catalyst precursors from precious metal refinery salts
Steven Cohen, Linda Kunz, Melvin Luetkens, Jr.

Preparing [Cl2RuCOD]x from refinery salts

1075 – Synthesis and application of heterogeneous Grubbs catalyst in camelina oil metathesis
Md J Abedin

“Gold of pleasure” metathesis

228 – Development of sequence-controlled polymers using a relay metathesis strategy
Will Gutekunst, Craig Hawker

A new and general strategy for the synthesis of sequence-defined polymers!

262 – Protein-polymer conjugates synthesized by ring opening metathesis polymerization
Heather D. Maynard

Tailor-made end-functionalized ROMP polymers for protein conjugation

865 – Solvent-free ruthenium catalysis in a ball mill: Exploring olefin metathesis from a mechanochemical perspective
Jean-Louis Do, Vjekoslav Štrukil, Tomislav Friščić

Metathesis meets liquid-assisted grinding

24 – Computational hints in olefin metathesis
Albert Poater, Steven Nolan, David Nelson, Simone Manzini, César Urbina-Blanco, Laura Falivene, Sai Vummaleti, Luigi Cavallo

A computational perspective of the factors effecting catalyst stability

982 – Exploring new ligand architectures for ruthenium olefin metathesis catalysts
Timothy Larocque, Anna Badaj, Gino Lavoie

Hemi-labile NHC-imines and low-valent phosphaalkenes meet ruthenium

51 – New fluorous ruthenium metathesis pre-catalysts: Synthesis and their employment in phase-transfer activation
Janos Balogh, Hassan Bazzi, John Gladysz

Fluorous analogues of Grubbs 3rd Gen!

175 – New well defined silica-supported tungsten oxo methyl synthesized by surface alkylation: Application in olefin and paraffin metathesis
Ali Hamieh, Yin Chen, Edy AbouHamad, Serena Goh, Lyndon Emsley, Jean-marie Basset

WOCl4 + silica support + selective methylation = metathesis catalyst

Also, don’t forget to stop by and visit us at ACS Expo Booth #1111 to learn more about olefin metathesis. The infamous Metathesis Challenge will be taking place and just for participating you can earn your very own Materia Metathesis T-shirt!! (While supply lasts)


Examining Polytopal Rearrangements around Ruthenium

May 31, 2014

Torker, S.; Khan, R.K.M.; Hoveyda, A.M. “The Influence of Anionic Ligands on Stereoisomerism of Ru Carbenes and Their Importance to Efficiency and Selectivity of Catalytic Olefin Metathesis Reactions” J. Am. Chem. Soc. 2014, 136, 3439-3455. For the past 15 years ruthenium catalysts have been a workhorse for olefin metathesis. Chemists have been able to tune […]

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Metathesis Featured at Modern Synthetic Methods & Chiral USA

May 1, 2014

Modern Synthetic Methods & Chiral USA Resort Orlando-Celebration Hotel, Florida USA May 19–21, 2014 Scientific Update has created a 3-day conference and exhibition to bridge a gap between industry and academia. Since industry rarely devises new synthetic methods to perform each step in the synthetic route, the event will provide a forum where industry and […]

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Cooperation between a Organometallic Complex and a Metalloenzyme

April 28, 2014

Denard, C. A.; Huang; H.; Bartlett, M. J., Lu, L.; Tan, Y.; Zhao, H.; and Hartwig, J. F. Angew. Chem. Int. Ed. 2014, 53, 465. Recently, the Hartwig group reported a tandem reaction in which a metalloenzyme and a metathesis catalyst worked cooperatively to yield products which cannot be generated in comparable yield by sequential […]

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Olefin Metathesis at the 247th ACS Meeting

February 27, 2014

The 247th ACS National Meeting and Exposition is less than a month away. The late winter/early spring event is set for Dallas, Texas from March 16-20, 2014. Olefin metathesis has no problem fitting into the meeting’s theme of “Chemistry and Materials for Energy” and keeping with tradition, we here at All Things Metathesis will provide […]

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Ruthenium Initiators Deliver Syndiotactic Polymers

December 16, 2013

Keitz, B.K.; Fedorov, A.; Grubbs, R.H. “Cis-Selective Ring-Opening Metathesis Polymerization with Ruthenium Catalysts” J. Am. Chem. Soc. 2012, 134, 2040-2043. Rosebrugh, L.E.; Marx, V.M.; Keitz, B.K.; Grubbs, R.H. “Synthesis of Highly Cis, Syndiotactic Polymers via Ring-Opening Metathesis Polymerization Using Ruthenium Metathesis Catalysts” J. Am. Chem. Soc. 2013, 135, 10032-10035. Controlling the stereochemistry of ring opening […]

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New Developments in Cis-Selective Ruthenium Metathesis Catalysts

November 22, 2013

Since Daryl Allen wrote his post in 2011 on the development of the first cis-selective ruthenium catalysts with chelating NHC ligands, a lot of activity and exciting new developments occurred in the area which warrants an update. After the pivalate complex 1 was published1, it was found that the nitrate derivative 2 is more stable and […]

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